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:: Volume 4, Issue 1 (3-2014) ::
Iran J Ped Hematol Oncol 2014, 4(1): 5-10 Back to browse issues page
Prevalence of transient hyperglycemia and diabetes mellitus in pediatric patients with acute leukemia
A Banihashem Dr, A Ghasemi Dr , N Ghaemi Dr, N Moazzen Dr, A Amirabadi Dr
Abstract:   (10481 Views)
Background The most common malignancy of children is Leukemia, accounting approximately one third of cancer diagnosis. Available data demonstrate improvement in survival of pediatric leukemia, so evaluation of side effects of treatment is very important. This study investigates hyperglycemia and diabetes mellitus prevalence in pediatric patients with acute leukemia. Materials and Methods This study was performed in children with acute leukemia. At the first admission, demographic data was collected and blood glucose and HbA1c levels were obtained. These tests examined at least two times during six months of follow up. Growth parameters and blood samples were obtained too. Result Twenty nine patients were examined three of them (10.3%) had diabetes mellitus and 5patients (17.2%) had transient hyperglycemia.Mean age of the patients was 6.26 years and nineteen Children (63%) were in preschool age. In preschool age children, incidence of hyperglycemia was meaningfully higher than school age children (p= 0.02). 24 of 29 patients (82.7%) were known case of acute lymphoblastic leukemia (ALL) and 5 patients (17.3%) were known case of acute myeloblastic leukemia (AML). No significant difference was found between sex groups. Also underweight was significant risk factor for hyperglycemia. Conclusion The prevalence of hyperglycemia was in the range of other similar studies in different parts of the world. Underweight and preschool ages were significant predictors of hyperglycemia.
Keywords: Acute Leukemia, Diabetes Mellitus, hyperglycemia
Full-Text [PDF 95 kb]   (719 Downloads)    
Type of Study: Research | Subject: Special
Received: 2014/03/15 | Accepted: 2014/03/15 | Published: 2014/03/15
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Banihashem A, Ghasemi A, Ghaemi N, Moazzen N, Amirabadi A. Prevalence of transient hyperglycemia and diabetes mellitus in pediatric patients with acute leukemia. Iran J Ped Hematol Oncol. 2014; 4 (1) :5-10
URL: http://ijpho.ssu.ac.ir/article-1-151-en.html

Volume 4, Issue 1 (3-2014) Back to browse issues page
Iranian Journal of Pediatric Hematology and Oncology
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