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Volume 13, Issue 2 (3-2023)
Iran J Ped Hematol Oncol 2023, 13(2): 161-165 |
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Dubick C, Sakhalkar V, Nair S, Boudreau M, Sakhalkar O. Pediatric B Cell Acute Lymphoblastic Leukemia presenting with Paraneoplastic Acute Disseminated Encephalomyelitis. Iran J Ped Hematol Oncol 2023; 13 (2) :161-165
URL: http://ijpho.ssu.ac.ir/article-1-699-en.html
URL: http://ijpho.ssu.ac.ir/article-1-699-en.html
Beverly Knight Olson Children’s Hospital, Atrium Health Navicent, Pediatric Hospitalist and Assistant Professor
Abstract: (428 Views)
Acute Disseminated Encephalomyelitis (ADEM) is a monophasic demyelinating disease most often triggered by infection or immunization, though associations with malignancy and stem cell transplant have been described. We described the case of a four-year-old boy with new-onset neurological symptoms associated with ADEM, acute leukemia, and equivocal evidence of Mycoplasma pneumoniae infection. He responded to a short course of antibiotics and chemotherapy for B cell acute lymphoblastic leukemia (B-ALL) that included a prolonged course of high dose steroids with immunosuppressive therapy. This case illustrated a possible association between paraneoplastic ADEM and leukemia in pediatric patients.
Type of Study: case report |
Subject:
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Received: 2022/01/10 | Accepted: 2022/12/29 | Published: 2023/03/19
Received: 2022/01/10 | Accepted: 2022/12/29 | Published: 2023/03/19
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