Volume 3, Issue 2 (6-2013)                   Iran J Ped Hematol Oncol 2013, 3(2): 73-77 | Back to browse issues page

XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Dorgalaleh A, Mahmoodi M, Varmaghani B, Kiani node F, Saeeidi Kia O, Alizadeh S, et al . Effect of Thyroid Dysfunctions on Blood Cell Count and Red Blood Cell Indice. Iran J Ped Hematol Oncol 2013; 3 (2) :73-77
URL: http://ijpho.ssu.ac.ir/article-1-115-en.html
Abstract:   (9614 Views)
Abstract Background Thyroid hormones have a crucial role in metabolism and proliferation of blood cells. Thyroid dysfunction induces different effects on blood cells such as anemia, erythrocytosis leukopenia, thrombocytopenia, and in rare cases causes’ pancytopenia. It also alter RBC indices include MCV, MCH, MCHC and RDW. Thus this study attempted to evaluate effect of hypo & hyperthyroidism on blood cell count and RBC indices. Materials and Methods This study performed on 102 patients with hypothyroid (14.1 years), 84 with hyperthyroid (15.6 years) and 118 healthy individuals (15.2 years) as control group. Initially patients TSH level of patients was determined by ELISA method, and then according to TSH ranges (0.3-5.5µIU/mL) patients were divided into two Hyperthyroidism (TSH<0.3µIU/mL) and hypothyroidism (TSH>5.5µIU/mL) groups. Then, complete blood count was measured by cell counter. Finally, obtained results were analyzed by SPSS software. Results Analyzes of obtained data revealed statistically significant difference between two groups of patients in RBC count, MCH, MCHC, RDW, HB and HCT(P-value<0.05), but the difference was not significant for WBC and PLT counts and MCV (P-value>0.05). Conclusion In case of patients with unknown hematological dysfunctions, must be evaluated for thyroid hormones.
Full-Text [PDF 95 kb]   (2519 Downloads)    
Type of Study: Research | Subject: Heart
Received: 2013/06/16 | Published: 2013/06/15

Add your comments about this article : Your username or Email:
CAPTCHA

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Iranian Journal of Pediatric Hematology and Oncology

Designed & Developed by : Yektaweb