Volume 2, Issue 3 (9-2012)                   Iran J Ped Hematol Oncol 2012, 2(3): 99-102 | Back to browse issues page

XML Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Küpeli S, Aldudak B, Baran A. Study of the Association between Congenital Heart Defects and Neuroblastoma in Abdominal Sonography. Iran J Ped Hematol Oncol. 2012; 2 (3) :99-102
URL: http://ijpho.ssu.ac.ir/article-1-78-en.html
Abstract:   (2586 Views)
Abstract Background A higher prevalence of congenital heart defects (CHD) in neuroblastoma patients in general population is reported in some publications, however, some authors did not find such an association. The evidence for this relation comes from the observation that, the neural crest cells accompany to the development of the heart and neuroblastoma as well. Materials and Methods We prospectively investigated this relation for the first time, in a cohort of 114 patients with CHD. Echocardiographic evaluations were made as two-dimensional morphological examination and the patients with CHD were evaluated with through physical examination, especially for the stigmata of neuroblastoma, telecardiogram and abdominal ultrasonography. Results In a period of 6 months, 114 children were diagnosed as CHD. Ventricular septal defect (VSD), atrial septal defect (ASD), pulmonary stenosis (PS) and tetrology of Fallot (TOF) were the most common diagnoses. We did not find any evidence for the association between CHD and neuroblastoma. Conclusion The possible association between the two entities was generally investigated by retrospective evaluation of echocardiographic studies in neuroblastoma patients. However, according to our preliminary results the presence of CHD is not a predilection for neuroblastoma. Detailed laboratory and radiological studies for neuroblastoma are not necessary in patients with CHD.
Full-Text [PDF 144 kb]   (847 Downloads)    
Type of Study: Research | Subject: Special
Received: 2012/09/16

Add your comments about this article : Your username or Email:

© 2019 All Rights Reserved | Iranian Journal of Pediatric Hematology and Oncology

Designed & Developed by : Yektaweb