TY - JOUR JF - SSU JO - Iran J Ped Hematol Oncol VL - 10 IS - 1 PY - 2020 Y1 - 2020/1/01 TI - Proptosis as Initial Presentation of Acute Lymphoblastic Leukemia in an Otherwise Healthy Child: A Case Report and Review of The Literature TT - پروپتوز به عنوان تظاهر اولیه لوسمی لنفوبلاستیک حاد در یک کودک سالم: گزارش مورد و مرور مطالعات پیشین N2 - Acute lymphocytic leukemia (ALL) is one of the frequent malignancies in pediatrics and involves bone marrow and extramedullary sites. Proptosis as extramedullary involvement of leukemia usually present in acute and chronic myeloid leukemia. It is extremely rare for ALL to present initially as proptosis.Here, a-21-month-old boy was presented with proptosis without any associated symptoms except lymphadenopathy. He was referred with the impression of malignancy from an ophthalmologist. After bone marrow biopsy which showed 33% blast cells, all positive for CD10, CD19, and CD79, the diagnosis of pre-B cell ALL was finally made. His symptoms were improved completely 16 days after starting standard protocol for ALL.Afterone-year follow-up, he was free of any symptoms.According to this initial presentation of ALL and no typical associated symptoms, it is important to make rapid diagnosis and start the treatment in the childhood. SP - 69 EP - 73 AU - Goudarzipour, Kourosh AU - Mohammadi, Ahmad AU - Taherian, Reza AU - Arabahmadi, Mehran AU - Behnam, Behdad AU - Ayoobi Yazdi, Niloofar AD - Brain Mapping Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran KW - Acute lymphoblastic leukemia KW - Proptosis KW - Childhood UR - http://ijpho.ssu.ac.ir/article-1-301-en.html DO - 10.18502/ijpho.v10i1.2171 ER -