Iranian journal of Pediatric Hematology and Oncology
Iranian journal of Pediatric Hematology and Oncology
Iran J Ped Hematol Oncol
Medical Sciences
http://ijpho.ssu.ac.ir
1
admin
2008-8892
2228-6993
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7
14
8888
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en
jalali
1391
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gregorian
2012
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online
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fulltext
en
The Efficacy of the EMLA Analgesic Cream in Compare with Placebo in Pediatric Oncology Lumbar Puncture
قلب
Heart
گزارش مورد
case report
The Efficacy of the EMLA Analgesic Cream in Compare with Placebo in Pediatric Oncology Lumbar Puncture
Qane M MD 1, Ghiliyan R MD2, Hashemi A MD3, Mirmohammadi SJ4 MD, Keshavarzi S MD 3, Yadegar Y MD3, Shefaie F MD1
1-Medical Student, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran
2- Department of Internal Medicine, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran
3-Department of Pediatric, Hematology, Oncology and Genetics Research Center, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran
4- Department of Occupational Medicine, Hematology, Oncology and Genetics Research Center, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran
Received: 28January 2012
Accepted: 10 April 2012
Abstract
Background
The present randomized clinical trial evaluated the efficacy of a topical lidocaine-prilocaine cream (EMLA) to relief pain during spinal puncture in pediatric oncology patients.
Materials and Methods
Sixty patients with malignancy candidate for spinal puncture were selected for this study. The patients were randomly allocated to two groups. Group A had topical EMLA cream and group B had placebo, which they received 60 to 90 minutes before spinal puncture. Pain score was rated using the Wong-Baker Faces rating score (0: no pain to 10: worst pain).
Results
Pain score does not reduce significantly in the topical EMLA cream in compared with placebo (p-value=0.126). No signs of infection were noted at the spinal puncture sites 24 or 48 hours after the procedure.
Conclusion
Results obtained from this study represents that the EMLA cream has not more analgesic effect than placebo in reducing the pain for spinal puncture.
Key words
Spinal Puncture, Pain, EMLA
Abstract
Background
The present randomized clinical trial evaluated the efficacy of a topical lidocaine-prilocaine cream (EMLA) to relief pain during spinal puncture in pediatric oncology patients.
Materials and Methods
Sixty patients with malignancy candidate for spinal puncture were selected for this study. The patients were randomly allocated to two groups. Group A had topical EMLA cream and group B had placebo, which they received 60 to 90 minutes before spinal puncture. Pain score was rated using the Wong-Baker Faces rating score (0: no pain to 10: worst pain).
Results
Pain score does not reduce significantly in the topical EMLA cream in compared with placebo (p-value=0.126). No signs of infection were noted at the spinal puncture sites 24 or 48 hours after the procedure.
Conclusion
Results obtained from this study represents that the EMLA cream has not more analgesic effect than placebo in reducing the pain for spinal puncture.
Spinal Puncture, Pain, EMLA
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http://ijpho.ssu.ac.ir/browse.php?a_code=A-10-1-88&slc_lang=en&sid=1
M
Qane
No
R
Ghiliyan
Yes
A
Hashemi
No
SJ
Mirmohammadi
No
S
Keshavarzi
No
Y
Yadegar
No
F
Shefaie
No