Iranian journal of Pediatric Hematology and Oncology
Iranian journal of Pediatric Hematology and Oncology
Iran J Ped Hematol Oncol
Medical Sciences
http://ijpho.ssu.ac.ir
1
admin
2008-8892
2228-6993
8
7
14
8888
13
en
jalali
1394
12
1
gregorian
2016
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1
6
1
online
1
fulltext
en
Evaluation Efficacy of Ferrous Sulfate Therapy on Headaches of 5-15 Years Old Iron Deficient Children with Migraine
قلب
Heart
پژوهشي
Research
<p>Abstract<br>
Background<br>
Some researches have shown the association between iron deficiency and migraine headache in adults. The aim of present study was to evaluate efficacy of ferrous sulfate treatment on migraine headaches of 5-15 years old migraineur children with iron deficiency.<br>
Materials and Methods<br>
In a quasi- experimental study, monthly frequency, severity, duration and disability of headaches of 5-15 years old migraineur<br>
children that prophylactic therapy was indicated in them and had iron deficiency who were referred to Pediatric eurology Clinic of Shahid Sadoughi University of Medical Sciences, Yazd, Iran between 2013 and 2015 and were treated with 2mg/kg/day topiramate plus 4mg/kg/day of ferrous sulfate for three consecutive months, were evaluated and headache characteristics before and after treatment were compared.<br>
Results<br>
In this study, 98 children with mean age of 9.72±3.19 were evaluated that 31children (31.6%) had iron deficiency. Monthly<br>
frequency (22.89±7.18 vs.14.5±4.56, P= 0.02), severity score (8.12± 1.76 vs. 5.03±1.15, P= 0.02) and disability score of<br>
headache (38.23±10.7vs. 30.12±7.46, P= 0.03) were more in children with iron deficiency. Iron therapy was effective in<br>
decreasing of monthlyfrequency 22.89± 7.18 vs. 10.13±4.51, P = 0.001), severity score (8.12±1.76 vs. 5.11±1.62, P =0.001),<br>
duration (2.14±1.23 vs.1.14±1.01, P= 0.001) and disability score of headache (38.23±10.7 vs. 22.87±8.65, P= 0.01). </p>
<p>Conclusion<br>
In children, iron deficiency increased monthly frequency, severity and disability of migraine headache and ferrous sulfate<br>
can be used as a safe and effective drug in migraine prophylaxis.</p>
Adverse effects, Malignancy, Pediatric, Complications, Vascular access device
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http://ijpho.ssu.ac.ir/browse.php?a_code=A-10-70-71&slc_lang=en&sid=1
R
Fallah
No
S
Zare Bidoki
No
M
Ordooei
Yes