en قلب Heart گزارش مورد case report The Efficacy of the EMLA Analgesic Cream in Compare with Placebo in Pediatric Oncology Lumbar Puncture Qane M MD 1, Ghiliyan R MD2, Hashemi A MD3, Mirmohammadi SJ4 MD, Keshavarzi S MD 3, Yadegar Y MD3, Shefaie F MD1 1-Medical Student, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran 2- Department of Internal Medicine, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran 3-Department of Pediatric, Hematology, Oncology and Genetics Research Center, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran 4- Department of Occupational Medicine, Hematology, Oncology and Genetics Research Center, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran Received: 28January 2012 Accepted: 10 April 2012 Abstract Background The present randomized clinical trial evaluated the efficacy of a topical lidocaine-prilocaine cream (EMLA) to relief pain during spinal puncture in pediatric oncology patients. Materials and Methods Sixty patients with malignancy candidate for spinal puncture were selected for this study. The patients were randomly allocated to two groups. Group A had topical EMLA cream and group B had placebo, which they received 60 to 90 minutes before spinal puncture. Pain score was rated using the Wong-Baker Faces rating score (0: no pain to 10: worst pain). Results Pain score does not reduce significantly in the topical EMLA cream in compared with placebo (p-value=0.126). No signs of infection were noted at the spinal puncture sites 24 or 48 hours after the procedure. Conclusion Results obtained from this study represents that the EMLA cream has not more analgesic effect than placebo in reducing the pain for spinal puncture. Key words Spinal Puncture, Pain, EMLA Abstract Background The present randomized clinical trial evaluated the efficacy of a topical lidocaine-prilocaine cream (EMLA) to relief pain during spinal puncture in pediatric oncology patients. Materials and Methods Sixty patients with malignancy candidate for spinal puncture were selected for this study. The patients were randomly allocated to two groups. Group A had topical EMLA cream and group B had placebo, which they received 60 to 90 minutes before spinal puncture. Pain score was rated using the Wong-Baker Faces rating score (0: no pain to 10: worst pain). Results Pain score does not reduce significantly in the topical EMLA cream in compared with placebo (p-value=0.126). No signs of infection were noted at the spinal puncture sites 24 or 48 hours after the procedure. Conclusion Results obtained from this study represents that the EMLA cream has not more analgesic effect than placebo in reducing the pain for spinal puncture. Spinal Puncture, Pain, EMLA 44 48 http://ijpho.ssu.ac.ir/browse.php?a_code=A-10-1-88&slc_lang=en&sid=1 M Qane No R Ghiliyan Yes A Hashemi No SJ Mirmohammadi No S Keshavarzi No Y Yadegar No F Shefaie No