en عمومى General گزارش مورد case report <div style="border:double windowtext 1.5pt; padding:1.0pt 4.0pt 1.0pt 0cm"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:Calibri,&quot;sans-serif&quot;"><span style="font-size:10.0pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;">Acute Disseminated Encephalomyelitis (ADEM) is a monophasic demyelinating disease most often triggered by infection or immunization, though associations with malignancy and stem cell transplant have been described. We described the case of a four-year-old boy with new-onset neurological symptoms associated with ADEM, acute leukemia, and equivocal evidence of Mycoplasma pneumoniae infection. He responded to a short course of antibiotics and chemotherapy for B cell acute lymphoblastic leukemia (B-ALL) that included a prolonged course of high dose steroids with immunosuppressive therapy. This case illustrated a possible association between paraneoplastic ADEM and leukemia in pediatric patients.</span></span></span></span></span></div> Encephalomyelitis, Leukemia, Paraneoplastic 161 165 http://ijpho.ssu.ac.ir/browse.php?a_code=A-10-927-1&slc_lang=en&sid=1 Collin Dubick collin.dubick@atriumhealth.org 0000-0003-4502-4009 Yes Beverly Knight Olson Children’s Hospital, Atrium Health Navicent, Pediatric Hospitalist and Assistant Professor Beverly Knight Olson Children’s Hospital, Atrium Health Navicent, Pediatric Hospitalist and Assistant Professor Vishwas Sakhalkar vishwas.sakhalkar@atriumhealth.org No Beverly Knight Olson Children’s Hospital, Atrium Health Navicent, Division of Hematology/Oncology. Mercer University School of Medicine, Macon, GA, Professor Beverly Knight Olson Children’s Hospital, Atrium Health Navicent, Division of Hematology/Oncology. Mercer University School of Medicine, Macon, GA, Professor Sushmita Nair sushmita.nair@atriumhealth.org No Beverly Knight Olson Children’s Hospital, Atrium Health Navicent, Division of Hematology/Oncology. Mercer University School of Medicine, Macon, GA, Assistant Professor Beverly Knight Olson Children’s Hospital, Atrium Health Navicent, Division of Hematology/Oncology. Mercer University School of Medicine, Macon, GA, Assistant Professor Mark Boudreau Mark.Boudreau@atriumhealth.org No Beverly Knight Olson Children’s Hospital, Atrium Health Navicent Beverly Knight Olson Children’s Hospital, Atrium Health Navicent Om Sakhalkar osakhalkar@augusta.edu No Beverly Knight Olson Children’s Hospital, Atrium Health Navicent Beverly Knight Olson Children’s Hospital, Atrium Health Navicent