Iranian journal of Pediatric Hematology and Oncology

en The Survival Rate of Leukemia Patients in Asian Regions: A Systematic Review and Meta-Analysis Study انکولوژی Oncology مروری سیستماتیک systematic review <div style="border: 1.5pt double windowtext; padding: 1pt 4pt; text-align: justify;">Background: Leukemia is one of the most common types of cancer worldwide, especially in children. The present research aims to comprehensively estimate leukemia cancer survival in Asian countries through a systematic review and meta-analysis. Materials and Methods: The current research is a systematic review and meta-analysis of leukemia patients' survival rates in Asian countries. Five databases ISI, PubMed, Scopus, ProQuest, and Google Scholar were used to search for relevant studies. Keywords were selected based on MeSH. The search for studies continued until February 1, 2023. The random-effects model was used to reduce the risk of bias in the studies. The Egger’s regression test was also used to evaluate the risk of publication bias. A total number of 73 papers were considered for the analysis. All analyses were performed by Comprehensive Meta-Analysis Version 2 software. Results: The overall one-year and five-year survival rates of the leukemia patients were 62.3% (95% CI: 60.9%-63.6%) and 46.7% (95% CI: 41.2%-52.3%), respectively. The results of the subgroup analysis revealed that the five-year survival rate of myeloid leukemia was 36.3% (95% CI: 35.8%-36.8%), while the five-year survival rate of lymphoid leukemia was 62.4% (95% CI: 58.2%-66.4%). The results of the overall 5-year survival rate of leukemia patients by age group showed that, in general, children have a higher survival rate than adults [63.3% (95% CI: 58.7%-67.6%) vs. 27.6% (95% CI: 23.2%-32.6%)]. Conclusion: In general, the survival rates of leukemia patients in Asian countries are very different. On the whole, however, the present study demonstrated that the five-year survival rate for leukemia patients in Asian countries has achieved a level of 46.7%, irrespective of variables such as age, cancer stage, or treatment protocol.</div> Asia, Leukemia, Lymphoid, Myeloid, Survival Rate 386 410 http://ijpho.ssu.ac.ir/browse.php?a_code=A-10-1141-1&slc_lang=en&sid=1 Reza Zare rezazr1080@gmail.com 0000-0001-9505-7226 No BSc of Operating Room, Larestan University of Medical Sciences, Larestan, Iran BSc of Operating Room, Larestan University of Medical Sciences, Larestan, Iran Hoda Haghshenas hoda76h@gmail.com 0000-0002-3684-3988 No Student Research Committee, Jahrom University of Medical Sciences, Jahrom, Iran Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran Sara Moghaddam sm.nursing@yahoo.com 0000-0003-3338-3936 No Instructor, Department of Nursing, Faculty of Nursing, Jahrom University of Medical Sciences, Jahrom, Iran Instructor, Department of Nursing, Faculty of Nursing, Jahrom University of Medical Sciences, Jahrom, Iran Ramin Avazpour raminavazpour@yahoo.com@gmail.com 0000-0003-0834-7810 No Shiraz University of Medical Sciences, Shiraz, Iran Shiraz University of Medical Sciences, Shiraz, Iran Hossein Kargar Jahromi hossein.kargarjahromy@gmail.com 0000-0002-2614-8885 No Research Center for Noncommunicable Disease, Jahrom University of Medical Sciences, Jahrom, Iran Research Center for Noncommunicable Disease, Jahrom University of Medical Sciences, Jahrom, Iran Hamed Delam hameddelam8@yahoo.com 0000-0003-2054-4892 Yes PhD Student of Epidemiology, Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran PhD Student of Epidemiology, Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran Ehsan Amini-Salehi ehsanaminisalehi1998@gmail.com 0000-0003-4985-2899 No Student Research Committee, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Student Research Committee, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran