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:: Volume 4, Number 1 (3-2014) ::
Iran J Ped Hematol Oncol 2014, 4(1): 1-4 Back to browse issues page
Relationship between ABO blood group and Acute Lymphoblastic Leukemia
Mrs F Tavasolian, Mrs E Abdollahi, Dr M Vakili, Mr A Amini
Abstract:   (3153 Views)
Acute lymphoblastic leukemia (ALL) constitute a family of genetically heterogeneous lymphoid neoplasms derived from B- and T-lymphoid progenitors. ALL affects both children and adults. Diagnosis is based on morphologic, immunophenotypic, and genetic features that allow differentiation from normal progenitors and other hematopoietic and nonhematopoietic neoplasms. The aim of this study was to investigate the association between ALL and ABO blood group. Material and method This is a case-control study that was carried out in Amir Oncology Hospital in Shiraz during 2011 to2013. The case group consisted of 293 patients with acute lymphoblastic leukemia. And compared with 300 subject in control group ( the age in the case group was between 2-5 year, and the age in the control group was between 2-45 year) .Statistical analyzes was done performed by chi –square test. The results was considered significant when p value <0.05. (CI:0.95) Results The ABO blood group distribution was 82(A), 59 (B), 24 (AB) and 128(O) in patient with Acute Lymphoblastic Leukemia and the blood group of 300 participants in the control group include, 63% (25) A, 69% (25.6) B, 18 % 06.8) AB and 101% (42.6) O. The ABO blood group distribution showed that there is significant differences between ABO blood group and patients with acute lymphoblastic leukemia . Conclusion This study showed significant association between ALL and ABO blood group and showed that blood group AB was associated with a higher risk of All (p value<0.001).
Keywords: Acute lymphoblastic leukemia, ABO blood group, Children
Full-Text [PDF 87 kb]   (693 Downloads)    
Type of Study: Research | Subject: Special
Received: 2014/03/15 | Accepted: 2014/03/15 | Published: 2014/03/15
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Tavasolian F, Abdollahi E, Vakili M, Amini A. Relationship between ABO blood group and Acute Lymphoblastic Leukemia. Iran J Ped Hematol Oncol. 2014; 4 (1) :1-4
URL: http://ijpho.ssu.ac.ir/article-1-150-en.html
Volume 4, Number 1 (3-2014) Back to browse issues page
Iranian Journal of Pediatric Hematology and Oncology
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