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:: Volume 4, Number 2 (6-2014) ::
Iran J Ped Hematol Oncol 2014, 4(2): 78-83 Back to browse issues page
A Fetal Hemolytic Anemia in a Child with Cytomegalovirus Infection
Dr S Hosseeini, Dr Sh Ansari, Dr E Kalantar, Dr M Sabzechian, Dr A Alibeik, Mr A Dorgalaleh
Abstract:   (17522 Views)
Background Autoimmune hemolytic anemia is a hematologic disorder that is rarely observed in infants and young children. Most of the cases are associated with viral or bacterial infections. In some cases, AIHA can be characterized by a chronic course and an unsatisfactory control of hemolysis, thus requiring prolonged immunosuppressive therapy. Case report Especially in children younger than 2 years of age, the clinical course of the disease may show either resistance to steroids or dependence on high-dose steroids. We report here an infant fatal autoimmune Conclusion This case suggests that investigation for the presence of CMV infection in infantile AIHA should be considered. Severe hemolysis is rare but could be a potentially life-threatening complication of CMV infection described mostly in immune compromised adults and children.
Keywords: Autoimmune hemolytic anemia, Cytomegalovirus, Direct anti globulin test, Viral load
Full-Text [PDF 90 kb]   (526 Downloads)    
Type of Study: Research | Subject: Special
Received: 2014/06/11 | Accepted: 2014/06/11 | Published: 2014/06/11
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Hosseeini S, Ansari S, Kalantar E, Sabzechian M, Alibeik A, Dorgalaleh A. A Fetal Hemolytic Anemia in a Child with Cytomegalovirus Infection. Iran J Ped Hematol Oncol. 2014; 4 (2) :78-83
URL: http://ijpho.ssu.ac.ir/article-1-166-en.html
Volume 4, Number 2 (6-2014) Back to browse issues page
Iranian Journal of Pediatric Hematology and Oncology
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