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:: Volume 5, Issue 4 (12-2015) ::
Iran J Ped Hematol Oncol 2015, 5(4): 193-205 Back to browse issues page
Health Related Quality of Life, Depression, Anxiety and Stress in
M AdibHajbaghery Dr, M Ahmadi Ms, S Poormansouri Mr
Abstract:   (1330 Views)



Awareness of factors associated with quality of life (QOL) in patients with beta-Thalassemia major (&beta-TM) is necessary to develop clinical programs in order to improve social support and QOL in &beta-TM patients. This study aimed to examine QoL, depression, anxiety, and stress in &beta-TM patients in Ahvaz, Iran.

Materials and Method

A cross-sectional study was conducted on173 &beta-TM patients aged &le12 years (12-18=55, &le19=118). Subjects were selected using a census method. Data collection instrument consisted of three parts including: demographic questions, SF-36 questionnaire and depression, anxiety, and stress scale (DAS-21).


The participants obtained a mean score of 64.38±18.20 for QOL, 6.4±5.1 for depression, 4.8±3.9 for anxiety, and 7.3±4.9 for stress. Significant relationship was found between QOL and employment (P=0.02) and education level (P<0.001). Patients in the age group of 12-18 years old had higher mean scores in the majority of QoL dimensions than those aged &le19. The mean scores of depression, anxiety, and stress were higher in patients aged &le19. No significant correlation was observed between QOL and depression, anxiety, stress scores, and other demographic variables. Moreover, a significant inverse correlation was found between QOL and depression (P<0.001,r= -0.62), anxiety (P<0.001,r= -0.55), and stress scores (P<0.001, r= -0.5) .


This study showed that &beta-TM patients experienced a considerable decrease both in their overall QoL and in its dimensions. A majority of the &beta-TM patients were also suffered from mild to severe depression, anxiety, and stress.

Full-Text [PDF 166 kb]   (413 Downloads)    
Type of Study: Research | Subject: Special
Received: 2015/11/23 | Accepted: 2015/11/23 | Published: 2015/11/23
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AdibHajbaghery M, Ahmadi M, Poormansouri S. Health Related Quality of Life, Depression, Anxiety and Stress in. Iran J Ped Hematol Oncol. 2015; 5 (4) :193-205
URL: http://ijpho.ssu.ac.ir/article-1-225-en.html

Volume 5, Issue 4 (12-2015) Back to browse issues page
Iranian Journal of Pediatric Hematology and Oncology
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