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:: Volume 6, Number 1 (3-2016) ::
Iran J Ped Hematol Oncol 2016, 6(1): 38-42 Back to browse issues page
Hematological Indices in Children with Non-organic Failure to Thrive: a Case-Control Study
Dr AH Jafari Nodoshan, Dr A Hashemi, Dr A Golzar , Dr F Karami, Mrs R Akhondzaraini
Abstract:   (688 Views)

Background
Non-organic failure to thrive (NFTT) is the most common cause of failure to thrive (FTT) which is attributed to inadequate
nutrition due to economic factors or parental neglect. NFTT can lead to a vicious cycle of poor and inadequate eating and severity of anemia. The aim of this study was to determine the hematological indices in children with NFTT.
Materials and Methods
In a cross sectional case control study, iron status and blood indices of forty five aged 6–60 months children with NFTT were
evaluated and compared with 45 healthy control children (with matching of age and sex).
Results
In this study, the prevalence of anemia was 48.9% in NFTT compared to 11.4% in the control group (p<0.001). Microcytic
anemia was significantly more prevalent among the subjects than the controls (77.8% versus 27.3%; p<0. 001). The serum iron level was 73.2 and 62.8 mcg/dl for the case and control groups (P=0.29). The ferritin level in the study group was 29.8 versus 35.47 ng/ml in the control group (p=0.227). The prevalence of iron deficiency anemia among children with mild, moderate, and severe underweight was 44.4%, 45.5%, and 48%, respectively. The highest prevalence of iron-deficiency
anemia was seen between age group of 12 and 24 months (p<0.05).
Conclusion
Based on the results of this study, a correlation between malnutrition and anemia was found. However, further
studies are needed to assess and confirm the current outcomes.

Keywords: Ferritin, Hematological indices, Non- Organic Failure to Thrive
Full-Text [PDF 140 kb]   (301 Downloads)    
Type of Study: Research | Subject: Special
Received: 2016/02/24 | Accepted: 2016/02/24 | Published: 2016/02/24
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Jafari Nodoshan A, Hashemi A, Golzar A, Karami F, Akhondzaraini R. Hematological Indices in Children with Non-organic Failure to Thrive: a Case-Control Study. Iran J Ped Hematol Oncol. 2016; 6 (1) :38-42
URL: http://ijpho.ssu.ac.ir/article-1-241-en.html
Volume 6, Number 1 (3-2016) Back to browse issues page
Iranian Journal of Pediatric Hematology and Oncology
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