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:: Volume 6, Number 4 (11-2016) ::
Iran J Ped Hematol Oncol 2016, 6(4): 216-227 Back to browse issues page
Complementary and Alternative Medicine in Pediatric Oncology Patients in South of Iran
Dr Mohammadreza Bordbar, Dr Roza Kamfiroozi, Dr Narges Fakhimi, Dr Zahra Jaafari, Dr Tahereh Zarei, Dr Sezaneh Haghpanah
MD Hematology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Abstract:   (537 Views)

Abstract
Background:

Children suffering from cancer frequently use complementary and alternative medicine (CAM). Most of people do not disclose using CAM to their physicians as they fear to be blamed or prohibited using them. Some of these products may interfere with the conventional remedies. The aim of this study was to investigate the frequency and characteristics of CAM use in pediatric oncology patients in 2 referral centers in south of Iran.
Materials and Methods:

In this cross-sectional study, all pediatric cancer patients (from 5 months to 18 years old) registered at two referral center (n=135) were investigated from January to July 2015 in Shiraz, southern Iran. Interview with their parents and completing the specific check list were done. Data were analyzed by SPSS v. 21 using Chi-square and Student t- test.
Results:

From 150 families approached, 135 (90%) completed the questionnaires. Overall, 114 (84.4%) children ever used a kind of CAM product while 92.6% sought faith healing. Concurrently, 81.1% of the CAM admitted users applied them with their conventional treatments. The most common used CAM products were Zinc (43.7%) and multivitamins (31.9%). None of the evaluated variables significantly influenced CAM use in the patients. Most of the patients (77%) introduced their physicians as the source of knowledge about CAM which was the most trusted source as well. About half of the patients (50.9%) did not inform their physicians to use these products.
Conclusion:

Oncologists should be aware of highly prevalent use of CAM among their patients. They should discuss with the families about the possible interactions of these products may have with chemotherapy drugs. A filled diary at regular intervals may help the physicians to monitor CAM use in their oncology patients.

Keywords: Cancer, Complementary and Alternative Medicine, Oncology, Pediatric
Full-Text [PDF 288 kb]   (207 Downloads)    
Type of Study: Research | Subject: Special
Received: 2015/08/23 | Accepted: 2016/01/5 | Published: 2016/10/29
References
1. Valji R, Adams D, Dagenais S, Clifford T, Baydala L, King WJ, et al. Complementary and alternative medicine: a survey of its use in pediatric oncology. Evid Based Complement Alternat Med. 2013;2013:527163. [Article]
2. Deng G, Cassileth B. Integrative oncology: an overview. Am Soc Clin Oncol Educ Book. 2014:233-42. [Article]
3. Braganza S, Ozuah PO, Sharif I. The use of complementary therapies in inner-city asthmatic children. J Asthma. 2003;40(7):823-7. [Article]
4. Hagen LE, Schneider R, Stephens D, Modrusan D, Feldman BM. Use of complementary and alternative medicine by pediatric rheumatology patients. Arthritis Rheum. 2003;49(1):3-6. [Article]
5. Soo I, Mah JK, Barlow K, Hamiwka L, Wirrell E. Use of complementary and alternative medical therapies in a pediatric neurology clinic. Can J Neurol Sci. 2005;32(4):524-8. [Article]
6. Wong AP, Clark AL, Garnett EA, Acree M, Cohen SA, Ferry GD, et al. Use of complementary medicine in pediatric patients with inflammatory bowel disease: results from a multicenter survey. J Pediatr Gastroenterol Nutr. 2009;48(1):55-60. [Article]
7. Ladas EJ, Rivas S, Ndao D, Damoulakis D, Bao YY, Cheng B, et al. Use of traditional and complementary/alternative medicine (TCAM) in children with cancer in Guatemala. Pediatr Blood Cancer. 2014;61(4):687-92. [Article]
8. Bishop FL, Prescott P, Chan YK, Saville J, von Elm E, Lewith GT. Prevalence of complementary medicine use in pediatric cancer: a systematic review. Pediatrics. 2010;125(4):768-76. [Article]
9. Martel D, Bussieres JF, Theoret Y, Lebel D, Kish S, Moghrabi A, et al. Use of alternative and complementary therapies in children with cancer. Pediatr Blood Cancer. 2005;44(7):660-8. [Article]
10. Huebner J, Prott FJ, Micke O, Muecke R, Senf B, Dennert G, et al. Online survey of cancer patients on complementary and alternative medicine. Oncol Res Treat. 2014;37(6):304-8. [Article]
11. Edwards GV, Aherne NJ, Horsley PJ, Benjamin LC, McLachlan CS, McKay MJ, et al. Prevalence of complementary and alternative therapy use by cancer patients undergoing radiation therapy. Asia Pac J Clin Oncol. 2014;10(4):346-53. [Article]
12. Fouladbakhsh JM, Balneaves L, Jenuwine E. Understanding CAM Natural Health Products: Implications of Use Among Cancer Patients and Survivors. J Adv Pract Oncol. 2013;4(5):289-306. [Article]
13. Asadi-Pooya AA, Shokouhyar S, Emami M, Sharifzade M. Perception and use of complementary and alternative medicine among patients with epilepsy. Archives of Neuroscience. 2014;1(2):60-6. [Article]
14. Babaeian M, Naseri M, Kamalinejad M, Ghaffari F, Emadi F, Feizi A, et al. Herbal Remedies for Functional Dyspepsia and Traditional Iranian Medicine Perspective. Iran Red Crescent Med J. 2015;17(11):e20741. [Article]
15. Barikani A, Beheshti A, Javadi M, Farahani S, Barikani F. Viewpoints of Patients in Qazvin Towards Complementary and Alternative Medicine. Biotechnology and Health Sciences. 2016;3(1). [Article]
16. Firoozabadi MD, Navabzadeh M, Roudsari MK, Zahmatkash M. Comparative efficacy trial of cupping and serkangabin versus conventional therapy of migraine headaches: A randomized, open-label, comparative efficacy trial. J Res Med Sci. 2014;19(12):1134-9. [Article]
17. Hasani-Ranjbar S, Zahedi HS, Abdollahi M, Larijani B. Trends in publication of evidence-based Traditional Iranian medicine in endocrinology and metabolic disorders. J Diabetes Metab Disord. 2013;12(1):49. [Article]
18. Hashempur MH, Heydari M, Mosavat SH, Heydari ST, Shams M. Complementary and alternative medicine use in Iranian patients with diabetes mellitus. J Integr Med. 2015;13(5):319-25. [Article]
19. MEHRPOOR G, OWLIA M, MIRJALILI M, FARZAN A, AKRAMI A. Complementary alternative medicine in rheumatologic diseases; data from outpatient clinics in Yazd, Iran. Journal of Case Reports in Practice (JCRP). 2014;2(3):92-6. [Article]
20. Pasalar M, Choopani R, Mosaddegh M, Kamalinejad M, Mohagheghzadeh A, Fattahi MR, et al. Efficacy and safety of jollab to treat functional dyspepsia: a randomized placebo-controlled clinical trial. Explore (NY). 2015;11(3):199-207. [Article]
21. TONEKABONI SH, NAEINI SJ, KHAJEH A, YAGHINI O, GHAZAVI A, GORJI FA. Use of Complementary and Alternative Medicine for Epileptic Children in Tehran: A Cross-Sectional Study (2009-2011). Iranian journal of child neurology. 2014;8(1):26. [Article]
22. Zohalinezhad ME, Hosseini-Asl MK, Akrami R, Nimrouzi M, Salehi A, Zarshenas MM. Myrtus communis L. Freeze-Dried Aqueous Extract Versus Omeprazol in Gastrointestinal Reflux Disease: A Double-Blind Randomized Controlled Clinical Trial. J Evid Based Complementary Altern Med. 2016;21(1):23-9. [Article]
23. Fahimi F, Hrgovic I, El-Safadi S, Munstedt K. Complementary and alternative medicine in obstetrics: a survey from Iran. Arch Gynecol Obstet. 2011;284(2):361-4. [Article]
24. Aghabati N, Mohammadi E, Pour Esmaiel Z. The effect of therapeutic touch on pain and fatigue of cancer patients undergoing chemotherapy. Evid Based Complement Alternat Med. 2010;7(3):375-81. [Article]
25. Ameri A, Heydarirad G, Rezaeizadeh H, Choopani R, Ghobadi A, Gachkar L. Evaluation of Efficacy of an Herbal Compound on Dry Mouth in Patients With Head and Neck Cancers: A Randomized Clinical Trial. J Evid Based Complementary Altern Med. 2016;21(1):30-3. [Article]
26. Esmaeili-Mahani S, Falahi F, Yaghoobi MM. Proapoptotic and Antiproliferative Effects of Thymus caramanicus on Human Breast Cancer Cell Line (MCF-7) and Its Interaction with Anticancer Drug Vincristine. Evid Based Complement Alternat Med. 2014;2014:893247. [Article]
27. Jafari N, Farajzadegan Z, Zamani A, Bahrami F, Emami H, Loghmani A, et al. Spiritual therapy to improve the spiritual well-being of Iranian women with breast cancer: a randomized controlled trial. Evid Based Complement Alternat Med. 2013;2013:353262. [Article]
28. Khazaei Koohpar Z, Entezari M, Movafagh A, Hashemi M. Anticancer Activity of Curcumin on Human Breast Adenocarcinoma: Role of Mcl-1 Gene. Iran J Cancer Prev. 2015;8(3):e2331. [Article]
29. Raeessi MA, Raeessi N, Panahi Y, Gharaie H, Davoudi SM, Saadat A, et al. [Article]
30. Samarghandian S, Hadjzadeh MA, Afshari JT, Hosseini M. Antiproliferative activity and induction of apoptotic by ethanolic extract of Alpinia galanga rhizhome in human breast carcinoma cell line. BMC Complement Altern Med. 2014;14:192. [Article]
31. Adams D, Dagenais S, Clifford T, Baydala L, King WJ, Hervas-Malo M, et al. Complementary and alternative medicine use by pediatric specialty outpatients. Pediatrics. 2013;131(2):225-32. [Article]
32. Huebner J, Micke O, Muecke R, Buentzel J, Prott FJ, Kleeberg U, et al. User rate of complementary and alternative medicine (CAM) of patients visiting a counseling facility for CAM of a German comprehensive cancer center. Anticancer Res. 2014;34(2):943-8. [Article]
33. Revuelta-Iniesta R, Wilson ML, White K, Stewart L, McKenzie JM, Wilson DC. Complementary and alternative medicine usage in Scottish children and adolescents during cancer treatment. Complement Ther Clin Pract. 2014;20(4):197-202. [Article]
34. Ezeome ER, Anarado AN. Use of complementary and alternative medicine by cancer patients at the University of Nigeria Teaching Hospital, Enugu, Nigeria. BMC Complement Altern Med. 2007;7:28. [Article]
35. Heath JA, Oh LJ, Clarke NE, Wolfe J. Complementary and alternative medicine use in children with cancer at the end of life. J Palliat Med. 2012;15(11):1218-21. [Article]
36. Lengacher CA, Bennett MP, Kip KE, Keller R, LaVance MS, Smith LS, et al. Frequency of use of complementary and alternative medicine in women with breast cancer. Oncol Nurs Forum. 2002;29(10):1445-52. [Article]
37. McCurdy EA, Spangler JG, Wofford MM, Chauvenet AR, McLean TW. Religiosity is associated with the use of complementary medical therapies by pediatric oncology patients. J Pediatr Hematol Oncol. 2003;25(2):125-9. [Article]
38. Montazeri A, Sajadian A, Ebrahimi M, Haghighat S, Harirchi I. Factors predicting the use of complementary and alternative therapies among cancer patients in Iran. Eur J Cancer Care (Engl). 2007;16(2):144-9. [Article]
39. Lissoni P, Messina G, Balestra A, Colciago M, Brivio F, Fumagalli L, et al. Efficacy of cancer chemotherapy in relation to synchronization of cortisol rhythm, immune status and psychospiritual profile in metastatic non-small cell lung cancer. In Vivo. 2008;22(2):257-62. [Article]
40. Lissoni P, Messina G, Parolini D, Balestra A, Brivio F, Fumagalli L, et al. A spiritual approach in the treatment of cancer: relation between faith score and response to chemotherapy in advanced non-small cell lung cancer patients. In Vivo. 2008;22(5):577-81. [Article]
41. Messina G, Lissoni P, Marchiori P, Bartolacelli E, Brivio F, Magotti L. Enhancement of the efficacy of cancer chemotherapy by the pineal hormone melatonin and its relation with the psychospiritual status of cancer patients. J Res Med Sci. 2010;15(4):225-8. [Article]
42. Messina G, Lissoni P, Rovelli F. Psychoimmunological analysis of cancer patients: correlation with the prognosis. Curr Aging Sci. 2012;5(3):263-72. [Article]
43. Broom A, Tovey P. The role of the Internet in cancer patients' engagement with complementary and alternative treatments. Health (London). 2008;12(2):139-55. [Article]
44. Mayadagli A, Aksu A, Goksel F, Gocen E, Karahacioglu E, Gumus M, et al. Determination of parameters affecting the use of complementary and alternative medicine in cancer patients and detection of prevalence of use. Afr J Tradit Complement Altern Med. 2011;8(4):477-82. [Article]
45. Shen J, Andersen R, Albert PS, Wenger N, Glaspy J, Cole M, et al. Use of complementary/alternative therapies by women with advanced-stage breast cancer. BMC Complement Altern Med. 2002;2:8. [Article]
46. Tuna S, Dizdar O, Calis M. The prevalence of usage of herbal medicines among cancer patients. J BUON. 2013;18(4):1048-51. [Article]
47. Walsh MC, Trentham-Dietz A, Schroepfer TA, Reding DJ, Campbell B, Foote ML, et al. Cancer information sources used by patients to inform and influence treatment decisions. J Health Commun. 2010;15(4):445-63. [Article]
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Bordbar M, Kamfiroozi R, Fakhimi N, Jaafari Z, Zarei T, Haghpanah S. Complementary and Alternative Medicine in Pediatric Oncology Patients in South of Iran. Iran J Ped Hematol Oncol. 2016; 6 (4) :216-227
URL: http://ijpho.ssu.ac.ir/article-1-271-en.html
Volume 6, Number 4 (11-2016) Back to browse issues page
Iranian Journal of Pediatric Hematology and Oncology
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