Volume 13, Issue 2 (3-2023)                   Iran J Ped Hematol Oncol 2023, 13(2): 161-165 | Back to browse issues page


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Beverly Knight Olson Children’s Hospital, Atrium Health Navicent, Pediatric Hospitalist and Assistant Professor
Abstract:   (442 Views)
Acute Disseminated Encephalomyelitis (ADEM) is a monophasic demyelinating disease most often triggered by infection or immunization, though associations with malignancy and stem cell transplant have been described. We described the case of a four-year-old boy with new-onset neurological symptoms associated with ADEM, acute leukemia, and equivocal evidence of Mycoplasma pneumoniae infection. He responded to a short course of antibiotics and chemotherapy for B cell acute lymphoblastic leukemia (B-ALL) that included a prolonged course of high dose steroids with immunosuppressive therapy. This case illustrated a possible association between paraneoplastic ADEM and leukemia in pediatric patients.
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Type of Study: case report | Subject: General
Received: 2022/01/10 | Accepted: 2022/12/29 | Published: 2023/03/19

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