Beverly Knight Olson Children’s Hospital, Atrium Health Navicent, Pediatric Hospitalist and Assistant Professor
Abstract: (442 Views)
Acute Disseminated Encephalomyelitis (ADEM) is a monophasic demyelinating disease most often triggered by infection or immunization, though associations with malignancy and stem cell transplant have been described. We described the case of a four-year-old boy with new-onset neurological symptoms associated with ADEM, acute leukemia, and equivocal evidence of Mycoplasma pneumoniae infection. He responded to a short course of antibiotics and chemotherapy for B cell acute lymphoblastic leukemia (B-ALL) that included a prolonged course of high dose steroids with immunosuppressive therapy. This case illustrated a possible association between paraneoplastic ADEM and leukemia in pediatric patients.
Type of Study:
case report |
Subject:
General Received: 2022/01/10 | Accepted: 2022/12/29 | Published: 2023/03/19