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Volume 13, Issue 2 (3-2023)
Iran J Ped Hematol Oncol 2023, 13(2): 79-86 |
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Jahanshahi A, Hiradfar A, Mahboubi S, Hosseinpour Feizi A, Shakeri Bavi A, Mostafavijabbari A, et al . The Predictive Value of Abdominal Ultrasonography Compared to CT Scan for the Evaluation of Pediatric Lymphoma. Iran J Ped Hematol Oncol 2023; 13 (2) :79-86
URL: http://ijpho.ssu.ac.ir/article-1-716-en.html
URL: http://ijpho.ssu.ac.ir/article-1-716-en.html
Amirreza Jahanshahi 
, Amirataollah Hiradfar , Shabnam Mahboubi , Abbasali Hosseinpour Feizi , Abolhassan Shakeri Bavi , Ali Mostafavijabbari , Hamid Reza Yousefi Nodeh , Sina Raeisi *
, Amirataollah Hiradfar , Shabnam Mahboubi , Abbasali Hosseinpour Feizi , Abolhassan Shakeri Bavi , Ali Mostafavijabbari , Hamid Reza Yousefi Nodeh , Sina Raeisi *
Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Abstract: (713 Views)
Background: Given the children's susceptibility to the harmful radiation of computerized tomography (CT) scans, ultrasonography can be a good alternative in staging pediatric lymphoma. The present study aimed to assess the predictive value of abdominal ultrasonography compared to CT scan in children with lymphoma.
Materials and Methods: Fifty-two children with confirmed lymphoma were included in the present cross-sectional analytical study and underwent CT scan. The staging was performed based on the involvement pattern, lymph nodes, liver involvement, spleen involvement, and lymph node sizes. Then, the patients underwent ultrasonography followed by re-staging. The data were analyzed by SPSS 26. p-value less than 0.05 was considered statistically significant.
Results: The included patients consisted of 32 (61.5%) boys and 20 (38.5%) girls with the median age of 6.0 years (4.3-8.0). The number of the patients with positive paraaortic lymphadenopathy, iliac chain lymphadenopathy, mesenteric lymphadenopathy, increased liver size, changed liver parenchyma, increased spleen size, changed spleen parenchyma, increased kidney size, and changed kidney parenchyma evaluated by sonography and CT scan were 24 (46.2%) and 26 (50.0%), 3 (5.8%) and 3 (5.8%), 34 (65.4%) and 34 (65.4%), 49 (94.2%) and 48 (92.3%), 23 (44.2%) and 23 (44.2%), 45 (68.2%) and 21 (31.8%), 48 (92.3%) and 48 (92.3%), 50 (96.2%) and 50 (96.2%), and 49 (94.2%) and 48 (92.3%), respectively (p ≤ 0.001). The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of abdominal ultrasonography staging compared to CT scan were 100%, more than 90%, more than 75%, and 100%, respectively.
Conclusion: Due to the sufficient sensitivity and specificity, ultrasonography has the potential to be applied instead of CT scan for the abdominal staging of pediatric lymphoma.
Materials and Methods: Fifty-two children with confirmed lymphoma were included in the present cross-sectional analytical study and underwent CT scan. The staging was performed based on the involvement pattern, lymph nodes, liver involvement, spleen involvement, and lymph node sizes. Then, the patients underwent ultrasonography followed by re-staging. The data were analyzed by SPSS 26. p-value less than 0.05 was considered statistically significant.
Results: The included patients consisted of 32 (61.5%) boys and 20 (38.5%) girls with the median age of 6.0 years (4.3-8.0). The number of the patients with positive paraaortic lymphadenopathy, iliac chain lymphadenopathy, mesenteric lymphadenopathy, increased liver size, changed liver parenchyma, increased spleen size, changed spleen parenchyma, increased kidney size, and changed kidney parenchyma evaluated by sonography and CT scan were 24 (46.2%) and 26 (50.0%), 3 (5.8%) and 3 (5.8%), 34 (65.4%) and 34 (65.4%), 49 (94.2%) and 48 (92.3%), 23 (44.2%) and 23 (44.2%), 45 (68.2%) and 21 (31.8%), 48 (92.3%) and 48 (92.3%), 50 (96.2%) and 50 (96.2%), and 49 (94.2%) and 48 (92.3%), respectively (p ≤ 0.001). The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of abdominal ultrasonography staging compared to CT scan were 100%, more than 90%, more than 75%, and 100%, respectively.
Conclusion: Due to the sufficient sensitivity and specificity, ultrasonography has the potential to be applied instead of CT scan for the abdominal staging of pediatric lymphoma.
Type of Study: Research |
Subject:
General
Received: 2022/03/21 | Accepted: 2022/12/22 | Published: 2023/03/19
Received: 2022/03/21 | Accepted: 2022/12/22 | Published: 2023/03/19
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