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Volume 16, Issue 4 (9-2026)
Iran J Ped Hematol Oncol 2026, 16(4): 1092-1098 |
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Cakmak Celik F, Kaya Narter F, Turgutoglu Yilmaz A, Caliskan E, Ay Y, Ceran Özcan C et al . Congenital Neuroblastoma with a Progressive Course in a Neonate. Iran J Ped Hematol Oncol 2026; 16 (4) : 7
URL: http://ijpho.ssu.ac.ir/article-1-927-en.html
URL: http://ijpho.ssu.ac.ir/article-1-927-en.html
Fatma Cakmak Celik * 
, Fatma Kaya Narter , Asli Turgutoglu Yilmaz , Emine Caliskan , Yilmaz Ay , Canan Ceran Özcan , Aysen Guler
, Fatma Kaya Narter , Asli Turgutoglu Yilmaz , Emine Caliskan , Yilmaz Ay , Canan Ceran Özcan , Aysen Guler
Neonatologist, Department of Pediatrics, Neonatology Division, University of Health Sciences, Hamidiye International Medical Faculty, Kartal Dr Lutfi Kirdar City Hospital, Istanbul, Türkiye
Abstract: (7 Views)
Background: Neuroblastoma can arise throughout the sympathoadrenal axis. It is one of the most common extracranial solid tumors in children, which accounts for about 6-10 % of all childhood cancers. Congenital neuroblastoma accounts for 5% of total neuroblastoma cases and is mostly diagnosed in the neonatal period. Treatment is individualized, and prognosis depends on many factors, including the grade of tumor. In the neonatal period, most cases of this condition regress spontaneously, with a good prognosis.
Case Presentation: A male infant born at 37 weeks of gestation with a birth weight of 3580 grams was admitted to our emergency service on the 19th day of his life. He had abdominal distention that started when the baby was 11 days old, which increased for the next five days. The case was considered to have infantile colic in another clinic and was followed until he was admitted to our hospital. Then, imaging techniques were used, and he was diagnosed with congenital neuroblastoma with massive hepatic involvement. The diagnosis was confirmed by pathologic evaluation in our Neonatal Intensive Care Unit (NICU). He was intubated until he died on the 38th day of his life due to disseminated intravascular coagulation and shock without responding to chemotherapy.
Conclusion: We want to emphasize that abdominal distention in the neonatal period should be evaluated carefully to diagnose and treat such life-threatening diseases as neuroblastoma.
Case Presentation: A male infant born at 37 weeks of gestation with a birth weight of 3580 grams was admitted to our emergency service on the 19th day of his life. He had abdominal distention that started when the baby was 11 days old, which increased for the next five days. The case was considered to have infantile colic in another clinic and was followed until he was admitted to our hospital. Then, imaging techniques were used, and he was diagnosed with congenital neuroblastoma with massive hepatic involvement. The diagnosis was confirmed by pathologic evaluation in our Neonatal Intensive Care Unit (NICU). He was intubated until he died on the 38th day of his life due to disseminated intravascular coagulation and shock without responding to chemotherapy.
Conclusion: We want to emphasize that abdominal distention in the neonatal period should be evaluated carefully to diagnose and treat such life-threatening diseases as neuroblastoma.
Article number: 7
Type of Study: case report |
Subject:
pediatrics
Received: 2025/01/9 | Accepted: 2026/09/14 | Published: 2026/09/20
Received: 2025/01/9 | Accepted: 2026/09/14 | Published: 2026/09/20
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